so, you see a problem with installshield apps...

what about launching the setup via another exe...

why you need to use run?
it's known that some installs won't work if ran with run.
with shell it ofcourse works little differently but would work.

if you need to use run... I think I would try something like:
run "start /wait setup.exe"

or:
run "explorer setup.exe"
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