I'm guessing a few possibilities:

1. The permissions on your netlogon share aren't right (I'm not sure how this would occur, but I would guess it's possible.)

2. You're not copying files properly to the netlogon share (via replication.)

3. The script is actually running, but errors out (because of permission problems) before you see anything happen. (We'd need to see your script to get this figured out.)

4. Also unlikely (provided #3 is false) -- problems with user permissions on the PC. You can test this by making users local admins.

Brian