I've done a bit of googling on this.

What happens if you hit Ctrl-P while in the program?

Maybe your AV is to blame... see this article.
http://www.wordbanter.com/showthread.php?t=42716

A couple of articles mention bad/corrupted profiles. Here's one with QBs.
http://community.intuit.com/posts/quickbooks-will-not-recognize-my-default-printer

A number of articles mention completely removing the printer and the drivers and reinstalling them as a fix.
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(... better days ahead)