I tested the 4.60 beta's ability to read the 64-bit branch of the HKLM\Software hive with the following code on a system running Windows 2003 R2 with Service Pack 2 and it did not read the non-redirected branch of the HKLM\Software hive:

$A = setoption("WOW64FileRedirection","OFF")
? ReadValue("HKEY_LOCAL_MACHINE\software\Diskeeper Corporation\Diskeeper","build")

This key exists in the 64 bit branch but not in the 32 bit branch so it is a good test.
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