Yes, I use it quite a bit, because most of my customers qualify as a Small Business.
What kind of things do you want to know? There are some differences... especially when it comes to wizards and preconfigured security. The big limiting factor of SBS is it has to be a domain controller, and it can be the only SBS in the domain. If you need to add other servers, they will have to be a regular install of Windows 2003/2000/NT Server.
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(... better days ahead)
