If you routine use EnumObject.exe or other method to dump the accounts. You could easily compare last months dump with the current one and know right away what accounts are no longer in the domain. The dump from last month would contain the home directory property data for the account. You would sinmply determine the account in the old dump that are not in the new dump and process the home directories.
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Home page: http://www.kixhelp.com/hb/