We use McAfee v7.00 with ePO 3.0.1, although I have also recently implemented Trend ServerProtect, since McAfee has caused a few problems on our Citrix/terminal servers. Also using Trend on file servers, as apparently Veritas Storage Replicator will not play nicely with McAfee either.
We use Antigen on our Exchange boxes, due to its handy ability to scan message queues as well as info stores.
Personally I don't like having such a disparate AV solution, but I've never been involved with the decision making processes, just been told to implement the decisions. 
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Breaker
