I have found from experience that most programs can be made to work without admin rights by either upgrading to the newest version or by tweaking permissions in the registry. Some apps may need only one or two keys opened up while others may need HKCR to opened. I strongly criticise any software that requires users to have elevated perms.
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Give a man a fish and he will be back for more. Slap him with a fish and he will go away forever.